DESCRIPTION Calcigard™ Two-to-One provides calcium and
magnesium in a 2:1 ratio from the same sources.
Both formulas, manufactured by Douglas
Laboratories®, are available with and without added
vitamin D.
FUNCTIONS The adult human body contains approximately 1,200
g of calcium, of which about 99% is present in the
skeleton, and 20-30 g of magnesium with about 60%
located in bone. The remaining 1% of total body
calcium and 40% of total body magnesium are found
in the soft tissues and play important roles in such
vital functions as nerve conduction, muscle
contraction, energy metabolism, blood clotting,
membrane permeability, and hormonal signaling.
Blood calcium levels are carefully maintained within
very narrow limits by the interplay of several
hormones (1,25-dihydroxy-cholecalciferol,
parathyroid hormone, calcitonin, estrogen, and
testosterone) which control calcium absorption and
excretion, as well as bone metabolism. The
intracellular levels of magnesium are also very tightly
regulated, since their alterations can have profound
effects on cardiac and skeletal muscle physiology.
Intestinal calcium absorption ranges from 15 to 75%
of ingested calcium. Adequate vitamin D status is
necessary for normal calcium absorption.
Magnesium absorption is independent of vitamin D
status and ranges from 30 to 60% of ingested
magnesium.
Bone is constantly turning over, through a continuous
process of formation and resorption. In children and
adolescents, the rate of formation of bone mineral
predominates over the rate of resorption. In later life,
resorption predominates over formation. Therefore,
in normal aging, there is a gradual loss of bone.
Osteoporosis afflicts a large proportion of the elderly
in developed countries. Caucasian and Asian women
typically have low peak bone densities, and are
therefore at the greatest risk of developing
osteoporosis. It is generally accepted that obtaining
enough dietary calcium throughout life can
significantly decrease the risk of developing
osteoporosis. Among other factors, such as regular
exercise, gender and race, calcium supplementation
during childhood and adolescence appears to be a
prerequisite for maintaining adequate bone density
later in life. But even elderly osteoporotic patients
can benefit significantly from supplementation with
dietary calcium and magnesium.
Calcigard Two-to-One provides highly beneficial
sources of both calcium and magnesium. They are
well absorbed and well tolerated.
Vitamin D is a key regulatory hormone for calcium
and bone metabolism. Adequate vitamin D intake is
important for ensuring normal calcium absorption
and maintaining proper calcium plasma levels.
People living in southern regions of the U.S. can
derive significant amounts of vitamin D from
sunlight dependent synthesis in the skin during the
summer, whereas people in the northern states have
to rely more on foods and supplements for adequate
vitamin D status. This is why Calcigard formulas are
available both with and without vitamin D.
INDICATIONS Calcigard Two-to-One may be useful dietary
supplements for those at risk for osteoporosis, or
anyone who wishes to increase their intake of
calcium and magnesium for maintaining good bone
health.
FORMULA (CA6) Serving Size 1 Tablet - Servings per Container 90
Each tablet contains:
